Endocrine Abstracts

Background: N-3 polyunsaturated fatty acids (PUFA), such as α linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to modify several key risk factors for cardiovascular disease, although n-6 PUFA arachidonic acid (AA) has important roles in inflammation. However, it is not clear whether the apparent protection of n-3 PUFA against cardiovascular disease has been found in diabetic patients.Methods: To clari...

Background: Many in vitro studies have suggested that oxidative stress induced by hyperglycemic condition has pivotal role for pathogenesis of vascular complications in diabetics. This study intended to evaluate oxidative stress and antioxidant potential in patients with type 2 diabetes mellitus (DM), and to clarify the relation between oxidative stress and metabolic derangements including chronic hyperglycemia.Materials and methods: We measured t...